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Body mass index is independently associated with xanthine oxidase activity in overweight/obese population
(Springer International Publishing, 2020)
Purpose: The pathophysiological mechanism of the relationship between xanthine oxidase (XO) activity and obesity has not been completely elucidated. Since inflammation and oxidative stress are regarded as key determinants ...
Association of oxidative stress and paraoxonase status with PROCAM risk score
(Pergamon-Elsevier Science Ltd, Oxford, 2009)
Objectives: Oxidative stress and paraoxonase activity play a significant role in the pathogenesis of cardiovascular disease (CVD). The Prospective Cardiovascular Munster (PROCAM) study evaluated the prevalence of CVD risk ...
Recovery of brain cholinesterases and effect on parameters of oxidative stres and apoptosis in quails (Coturnix japonica) after chlorpyrifos and vitamin B1 administration
(Elsevier Ireland Ltd, 2021)
Chlorpyrifos is a extensively used organophosphate pesticide (OP). In this study, we closely looked into neurotoxicity of CPF and effect of vitamin B1, by checking the levels of cholinesterases, determining the activity ...
Polychlorinated biphenyls as oxidative stress inducers in liver of subacutely exposed rats: Implication for dose-dependence toxicity and benchmark dose concept
(Academic Press Inc Elsevier Science, San Diego, 2015)
Hepatotoxicity is one of the well-documented adverse health effects of polychlorinated biphenyls (PCBs)persistent organic pollutants widely present in the environment. Although previous studies suggest possible role of ...
Oxidative stress and paraoxonase 1 status in acute ischemic stroke patients
(Elsevier Ireland Ltd, Clare, 2015)
Objective: The connection of oxidative stress with dyslipidemia creates a newly-emerging atherosclerosis risk factor involved in acute ischemic stroke development. This study analyzed the influence of oxidative stress on ...
Insight into the oxidative stress induced by lead and/or cadmium in blood, liver and kidneys
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Besides being important occupational hazards, lead and cadmium are nowadays metals of great environmental concern. Both metals, without any physiological functions, can induce serious adverse health effects in various ...
Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Catechol groups can be involved in redox cycling accompanied by generation of reactive oxygen species (ROS) which may lead to oxidative damage of cellular macromolecules including DNA. The objective of this investigation ...
Association of paraoxonase 1 and oxidative stress with acute kidney injury in premature asphyxiated neonates
(Elsevier Ireland Ltd, Clare, 2017)
Objectives: Acute kidney injury (AKI) is defined as a decrease in glomerular filtration rate with an increase in serum creatinine (sCr). Perinatal asphyxia (PNA) may be etiological factor for AKI with oxidative stress also ...
Older age and HDL-cholesterol as independent predictors of liver fibrosis assessed by BARD score
(Edizioni Minerva Medica, Turin, 2019)
BACKGROUND: It is known that non-alcoholic fatty liver disease (NAFLD), and in particular non-alcoholic steatohepatitis, can progress to advanced fibrosis. However, pathophysiological mechanisms implicated in this evolution ...
DNA, protein and lipid oxidative damage in tissues of spontaneously hypertensive versus normotensive rats
(Elsevier Ltd, 2021)
Oxidative damage to protein and lipid macromolecules in target organs in hypertension has been recognized as a major factor contributing to cardiovascular, cerebrovascular, and renal diseases. Data on protein and lipid ...