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Involvement of toxic metals and PCBs mixture in the thyroid and male reproductive toxicity: In silico toxicogenomic data mining
(Elsevier, 2023)
Toxicological research is mostly limited to considering the effects of a single substance, even though the real exposure of people is reflected in their daily exposure to many different chemical substances in low-doses. ...
Long-term effects of chromium on morphological and immunological parameters of Wistar rats
(Elsevier, 2019)
Abstract
Hexavalent chromium raises high concern because of its wide industrial applications and reported toxicity. Long-term (135 days) oral exposure of Wistar rats to chromium in the form of K2Cr2O7 (exposed group~20 mg/kg/day) ...
Relationship between bone resorption, oxidative stress and inflammation in severe COPD exacerbation
(Pergamon-Elsevier Science Ltd, Oxford, 2013)
Background: The natural course of chronic obstructive pulmonary disease (COPD) is complicated by the development of systemic consequences and co-morbidities. Increasing evidence indicates that COPD and osteoporosis are ...
The Association of Serum Iron-Binding Proteins and the Antioxidant Parameter Levels in Age-Related Macular Degeneration
(Taylor & Francis Inc, Philadelphia, 2018)
Purpose: Age-related macular degeneration (AMD) is the leading cause of the irreversible central visual loss among the elderly in the developed countries. Iron is considered a potent generator of the oxidative damage whose ...
Differences in antioxidant potential of chalcones in human serum: In vitro study
(Elsevier Ireland Ltd, 2020)
An imbalance between oxidants and antioxidants in favour of oxidants, potentially leading to damage, is termed oxidative stress. Antioxidants (AO), either enzymatic or non-enzymatic, are the ones that can reduce diverse ...
Effect of astaxanthin supplementation on muscle damage and oxidative stress markers in elite young soccer players
(Edizioni Minerva Medica, Turin, 2012)
Aim. The purpose of the current study was to examine the effect of Astaxanthin (Asx) supplementation on muscle enzymes as indirect markers of muscle damage, oxidative stress markers and antioxidant response in elite young ...
Hyperlipidemia, oxidative stress, and intima media thickness in children with chronic kidney disease
(Springer, New York, 2013)
The roles of dyslipidemia and oxidative stress in the early phases of atherosclerosis were tested in children with chronic kidney disease (CKD). Intima media thickness of common carotid arteries (cIMT) is used as a measure ...
The effect of inhibition of nitric oxide synthase on aluminium-induced toxicity in the rat brain
(General Physiol And Biophysics, Bratislava, 2009)
The goal of the present study was to examine the effectiveness of a non-specific nitric oxide synthase (NOS) inhibitor N-nitro-L-arginine methyl ester (L-NAME) to modulate the toxicity of aluminium chloride (AlCl3). Rats ...
Association of oxidative stress and paraoxonase status with PROCAM risk score
(Pergamon-Elsevier Science Ltd, Oxford, 2009)
Objectives: Oxidative stress and paraoxonase activity play a significant role in the pathogenesis of cardiovascular disease (CVD). The Prospective Cardiovascular Munster (PROCAM) study evaluated the prevalence of CVD risk ...
Xanthine oxidase and uric acid as independent predictors of albuminuria in patients with diabetes mellitus type 2
(Springer-Verlag Italia Srl, Milan, 2018)
Xanthine oxidase (XO) is an important enzyme responsible for conversion of purine bases to uric acid and represents the major source of reactive oxygen species (ROS) production in circulation. Since pathophysiological ...