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Simultaneous Analysis of Irbesartan and Hydrochlorothiazide: An Improved HPLC Method with the Aid of a Chemometric Protocol
(MDPI, Basel, 2012)
Experimental design method was used for HPLC determination of irbesartan and hydrochlorothiazide in combined dosage forms. The traditional approach for optimization of experiments is time-consuming, involves a large number ...
A full factorial design in the formulation of diazepam parenteral nanoemulsions: Physicochemical characterization and stability evaluation / Pun faktorski dizajn u formulaciji parenteralnih nanoemulzija sa diazepamom - fizičkohemijska karakterizacija i procena stabilnosti
(Univerzitet u Nišu - Tehnološki fakultet, Leskovac, 2015)
Using the experimental design methodology, we have developed and characterized nanoemulsions for a parenteral delivery using diazepam as a model drug. The formulations containing 20 or 30% (w/w) of medium chain triglycerides ...
Physicochemical Factors Governing the Partition of Pramipexole and Its Five Impurities in Microemulsion Liquid Chromatographic Systems
(Soc Brasileira Quimica, Sao Paulo, 2012)
Microemulsions when used as mobile phases represent a very powerful chromatographic tool due to their polyphase structure. The aim of this study was to investigate the influence of the mobile phase composition and resulting ...
Mikro- i nanostrukturirani emulzioni sistemi na bazi polihidroksilnih surfaktanata za isporuku aceklofenaka u/kroz kožu primenom hemijskih pojačivača penetracije i mikroigala
(Универзитет у Београду, Фармацеутски факултет, 2019)
Imajući na umu ograničenu biološku raspoloţivost i posledično terapijski efekat nesteroidnih antiinflamatornih lekova (NSAIL) primenjenih na koţi, cilj doktorske disertacije bio je razvoj, optimizacija i sveobuhvatna ...
Uticaj ekstrakta lista artičoke na metabolizam atorvastatina i optimizacija metoda tečne hromatografije za praćenje nastalih metabolita u biološkom materijalu / Influence of artichoke leaf extract on atorvastatin metabolism and optimization of liquid chromatography methods for determination of atorvastatin and metabolites in biological material
(Универзитет у Београду, Фармацеутски факултет, 2015)
Atorvastatin pripada grupi antihiperlipidemijskih lekova poznatih pod nazivom statini.Osnovni mehanizam delovanja ovih lekova je specifična, kompetitivna i reverzibilnainhibicija HMG-CoA reduktaze, enzima koji je značajan ...
Funkcionalnost hitozana u formulaciji alginat-hitozan mikročestica kao nosača za nesteroidne antiinflamatorne lekove
(Универзитет у Београду, Фармацеутски факултет, 2013)
Prednosti mikročestica u odnosu na konvencionalne nosače lekovitih supstanci ogledajuse u sferičnom obliku, velikom odnosu površine i volumena, mikrometarskimdimenzijama, raznovrsnosti materijala za njihovu izradu i ...
Karakterizacija sistema tečne hromatografije hidrofilnih interakcija sa UV i MS/MS detekcijom u analitici i bioanalitici olopatadina
(Универзитет у Београду, Фармацеутски факултет, 2018)
Cilj doktorske disertacije bio je da se kroz sveobuhvatnu karakterizaciju sistema tečne hromatografije hidrofilnih interakcija (eng. Hydrophilic Interaction Liquid Chromatography – HILIC) sa UV (eng. Ultraviolet) i MS/MS ...
Using experimental design in optimisation of VIS spektrophotometric method of investigation feroglicin sulfate in Orferon retard tablets / Primena eksperimentalnog dizajna u optimizaciji VIS spektrofotometrijske metode za određivanje feroglicin sulfata u Orferon retard tabletama
(Savez farmaceutskih udruženja Srbije, Beograd, 2004)
Iron preparations are used in the treatment or prophylaxis of sideropenic anemia developed due to insuficiency of iron in the body. They can be used orally (tablets, capsules, suspensiones, wines ) and parenterally. The ...
Central Composite Design with/without Artificial Neural Networks in Microemulsion Liquid Chromatography Separation Robustness Testing
(Slovensko Kemijsko Drustvo, Ljubljana, 2009)
In past few years, for overcoming some analytical problems in liquid chromatography, the microemulsion as eluent was employed. Due to the strict regulatory requirements, robustness testing became important especially when ...
An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media
(Taylor & Francis Ltd, Abingdon, 2006)
The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release ...