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Study of forced degradation behavior of Eletriptan hydrobromide by LC and LC-MS and development of stability-indicating method
(Elsevier Science BV, Amsterdam, 2009)
The objective of the present study was to report the stability profile of novel antimigrain drug Eletriptan hydrobromide based on the information obtained from forced degradation studies. The drug was subjected to acid ...
The impact of primary packaging on the quality of parenteral products
(Pergamon-Elsevier Science Ltd, Oxford, 2008)
The unique approach in manufacturing of pharmaceutical dosage forms of active substances known to be unstable in aqueous solution is the introduction of lyophilization process. Nevertheless, these products must be reconstituted ...
First-order UV-derivative spectrophotometry in the analysis of omeprazole and pantoprazole sodium salt and corresponding impurities
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
The first-order UV-derivative spectrophotometry, applying zero-crossing method was developed for the determination of omeprazole (OM), omeprazole sulphone (OMS), pantoprazole sodium salt (PANa), and N-methylpantoprazole ...
Determination of bifonazole in creams containing methyl- and propyl p-hydroxybenzoate by derivative spectrophotometric method
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
A second order derivative spectrophotometric method for the determination of bifonazole in the presence of methyland propyl p-hydroxybenzoate as preservatives has been developed. The determination was performed in a 0.1 M ...
Quality by Design oriented development of hydrophilic interaction liquid chromatography method for the analysis of amitriptyline and its impurities
(Elsevier Science BV, Amsterdam, 2019)
This paper presents integration of Quality by Design concept in the development of hydrophilic interactions liquid chromatographic methods for analysis of amitriptyline and its impurities (A, B, C, and F). This is the first ...
Analysis of potential genotoxic impurities in rabeprazole active pharmaceutical ingredient via Liquid Chromatography-tandem Mass Spectrometry, following quality-by-design principles for method development
(Elsevier Science BV, Amsterdam, 2018)
A novel Liquid Chromatography-tandem mass spectrometry (LC-MS/MS) method is presented for the quantitative determination of two potential genotoxic impurities (PGIs) in rabeprazole active pharmaceutical ingredient (API). ...
Evaluation of impurities level of perindopril tert-butylamine in tablets
(Elsevier Science BV, Amsterdam, 2007)
Perindopril tert-butylamine is a new member of angiotensin-converting enzyme inhibitors group used in the treatment of hypertension and heart failure. In this paper, the evaluation of reversed-phase high-performance liquid ...
Analysis of phenolics in wine by high performance thin-layer chromatography with gradient elution and high resolution plate imaging
(Elsevier Science BV, Amsterdam, 2015)
Health benefits of wine, especially with red wine, have been linked to the presence of a wide range of phenolic antioxidants. Thus, the aim of this study was to develop a simple, high performance thin layer chromatographic ...
Spectrophotometric determination of nizatidine in pharmaceutical formulations
(Journal of Pharmaceutical and Biomedical Analysis, 1995)
Application of Analytical Quality by Design concept for bilastine and its degradation impurities determination by hydrophilic interaction liquid chromatographic method
(Elsevier Science BV, Amsterdam, 2016)
This paper deals with the development of hydrophilic interaction liquid chromatographic (HILIC) method for the analysis of bilastine and its degradation impurities following Analytical Quality by Design approach. It is the ...