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Forced degradation study of torasemide: Characterization of its degradation products
(Taylor & Francis Inc, Philadelphia, 2013)
Torasemide was subjected to forced degradation studies. Stress conditions were varied concerning hydrolysis (acid, base, and neutral), oxidation, photolysis, and thermal degradation in order to identify the potential ...
Ibuprofen delivery: Pharmaceutical nanotechnology approach
(Nova Science Publishers, Inc., 2013)
Ibuprofen is non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of pain and inflammation related with rheumatoid arthritis, osteoarthritis, dysmenorrhea, headaches, muscle pain, common cold, after ...
A hospital pharmacist led assessment of the persistence to bisphosphonates, vitamin D and calcium supplements in postmenopausal women with osteoporosis
(John Libbey Eurotext, 2016)
Objectives: To assess and compare the point prevalence of postmenopausal women with osteoporosis persistent to bisphosphonates, vitamin D and calcium supplements between those who have already been provided with multidisciplinary ...
Eight red cell enzymes polymorphisms in the Slovakian ethnic group of Yugoslavia.
(Gene geography : a computerized bulletin on human gene frequencies, 1988)
The polymorphisms of eight red cell enzymes were studied in 211 unrelated voluntary blood donors from the ethnic group of Slovakians (Yugoslavia). Only common phenotypes were detected, which are usually present in European ...
Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil-indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease
(Elsevier France-Editions Scientifiques Medicales Elsevier, Issy-Les-Moulineaux, 2014)
The design, synthesis, and pharmacological evaluation of donepezil indolyl based amines 7-10, amides 12-16, and carboxylic acid derivatives 5 and 11, as multipotent ASS234 analogs, able to inhibit simultaneously cholinesterase ...
Highly efficient Michael-type addition of acetaldehyde to beta-nitrostyrenes by whole resting cells of Escherichia coli expressing 4-oxalocrotonate tautomerase
(Elsevier Sci Ltd, Oxford, 2013)
A novel whole cell system based on recombinantly expressed 4-oxalocrotonate tautomerase (4-OT) was developed and shown to be an effective biocatalyst for the asymmetric Michael addition of acetaldehyde to beta-nitrostyrenes. ...
An investigation of diclofenac sodium release from cetylpyridinium chloride-modified natural zeolite as a pharmaceutical excipient
(Elsevier Science BV, Amsterdam, 2013)
In this paper, investigations of zeolite - cationic surfactant - drug composites as drug carriers were performed. For that purpose, after adsorption of the model drug - diclofenac sodium (DS) onto composites obtained by ...
Spray coating as a powerful technique in preparation of solid dispersions with enhanced desloratadine dissolution rate
(Taylor & Francis Ltd, Abingdon, 2013)
Solid dispersion systems have been widely used to enhance dissolution rate and oral bioavailability of poorly water-soluble drugs. However, the formulation process development and scale-up present a number of difficulties ...
Comparative Study of Spasmolytic Properties, Antioxidant Activity and Phenolic Content of Arbutus unedo from Montenegro and Greece
(Wiley-Blackwell, Malden, 2011)
Arbutus unedo leaf is used traditionally for gastrointestinal complaints. Ethanol extracts from Arbutus unedo collected in both Montenegro (AuM) and Greece (AuG) were found to decrease the ileal basal tonus, with AuG ...
The Effects of Anionic, Cationic, and Nonionic Surfactants on Acid-Base Equilibria of ACE Inhibitors
(Amer Chemical Soc, Washington, 2013)
The pK(a) values of ACE inhibitors captopril, cilazapril, enalapril, fosinopril, lisinopril, perindopril, quinapril, ramipril, and zofenopril were determined by potentiometry. Because to the presence of single or several ...