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Fosinopril-sodium and its degradation product analysis in Monopril® tablets
(Slovensko Kemijsko Drustvo, 2003)
The reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed for the simultaneous determination of fosinopril-sodium and its degradation product in Monopril® tablets. The chromatographic ...
Simulataneous determination of nimesulide and its impurities in pharmaceutical formulations by reversed-phase high-performance liquid chromatography
(Slovensko Kemijsko Drustvo, Ljubljana, 2007)
A simple, rapid and reproducible reversed-phase high-performance liquid chromatography method for the analysis of nimesulide and its impurities both in the bulk drug and pharmaceutical formulations is reported. The method ...
Application of the response surface methodology for RP-HPLC analysis of lidocaine and cetrimonium bromide
(Slovensko Kemijsko Drustvo, Ljubljana, 2004)
The successful analysis of drugs in complex pharmaceutical formulations by reversed-phase high performance liquid chromatography (RP-HPLC) relies upon the optimization of the chromatographic conditions, the sample preparation ...
Experimental design in chromatographic analysis of pramipexole and its impurities
(Slovensko Kemijsko Drustvo, Ljubljana, 2007)
Pramipexole is a dopamine D2-agonist/antiparkinsonian agent in which BI-II 546 CL, BI-II 751 xx and 2-amino benzothiazole are commonly found as impurities. Due to the lack of analytical data on pramipexole and its related ...
Statistical Optimization of Reverse Phase High Performance Liquid Chromatography for the Analysis of Caffeine Paracetamol and its Degradation Product p-aminophenol
(Slovensko Kemijsko Drustvo, Ljubljana, 2008)
Paracetamol, analgoantipyretic and anti-inflammatory drug, is available in numerous pharmaceutical formulations in common combination with caffeine and some other drug substances. p-aminophenol is paracatamol's process-related ...
Spectrofluorimetric and HPLC Determination of Morin in Human Serum
(Slovensko Kemijsko Drustvo, Ljubljana, 2009)
Morin is a flavonol antioxidant. In ethanol-water mixtures (70 wt% of ethanol) it reacts with Al(3+) to give Al(Morin)(2) in the pH range 3-6. The conditional stability constant of this complex at 298 K was found to be log ...
Central Composite Design with/without Artificial Neural Networks in Microemulsion Liquid Chromatography Separation Robustness Testing
(Slovensko Kemijsko Drustvo, Ljubljana, 2009)
In past few years, for overcoming some analytical problems in liquid chromatography, the microemulsion as eluent was employed. Due to the strict regulatory requirements, robustness testing became important especially when ...