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Chemical composition of volatile compounds of eight Geranium L. species from Vlasina plateau
(Institute of Botany and Botanical Garden Jevremovac, Belgrade, 2018)
The Vlasina plateau shows significant floristic diversity counting 956 species of which 91 may be categorized as endangered
in the flora of Serbia. The genus Geranium is present in the
flora of this region with few species ...
Fatty acid composition including trans-fatty acids in salty snack food from the Serbian market
(Srpsko hemijsko društvo, Beograd, 2018)
The rapid increase in the consumption of salty snack products has led to increased concern about their composition and nutritional value. The aim of this study was to investigate the fat content and fatty acid profile in ...
Prediction of in vivo Bioavailibility by in vitro Characterization of Ethylenediamine Dipropanoic Acid Derivatives with Cytotoxic Activity
(Slovensko Kemijsko Drustvo, Ljubljana, 2018)
O,O'-diethyl-(S, S)-ethylenediamine-N, N'-di-2-(3-cyclohexyl) propanoate (DE-EDCP) is novel substance with cytotoxic activity in human leukemic cells. The aim of this study has been to predict in vivo bioavailability of ...
Molecular modeling and analysis of the 3D pharmacophore structure of the selective PI3K-α inhibitors as antitumor agents / Molekulsko modelovanje i analiza 3D-strukture farmakofore selektivnih PI3K-α inhibitora kao antitumorskih agenasa
(Savez farmaceutskih udruženja Srbije, Beograd, 2018)
The importance of the activation of phosphatidylinositol-3-kinase (PI3K) in the processes of tumor cell formation and growth has brought great interest in the development of new antitumor drugs that inhibit the PI3K-Akt ...
A perspective on multi-target drug discovery and design for complex diseases
(Springeropen, London, 2018)
Diseases of infection, of neurodegeneration (such as Alzheimer's and Parkinson's diseases), and of malignancy (cancers) have complex and varied causative factors. Modern drug discovery has the power to identify potential ...
Matrix Metalloproteinase-9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in Sepsis after Major Abdominal Surgery
(Hindawi Ltd, London, 2018)
Background. The role of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) in sepsis after major abdominal surgery and sepsis-associated organ dysfunction is unexplored. Materials ...
Uncertainty of Measurement in Laboratory Medicine
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2018)
An adequate assessment of the measurement uncertainty in a laboratory medicine is one of the most important factors for a reliable interpretation of the results. A large number of standards and guidelines indicate the need ...
Isolation and Determination of Fomentariol: Novel Potential Antidiabetic Drug from Fungal Material
(Hindawi Ltd, London, 2018)
Diabetes mellitus is one of the leading world's public health problems. Therefore, it is of a huge interest to develop new antidiabetic drugs. Apart from traditional therapy of diabetes, nowadays, importance is given to ...
Overview of Cadmium Thyroid Disrupting Effects and Mechanisms
(MDPI, Basel, 2018)
Humans are exposed to a significant number of chemicals that are suspected to produce disturbances in hormone homeostasis. Hence, in recent decades, there has been a growing interest in endocrine disruptive chemicals. One ...
Pro-oxidants and antioxidants in retinopathy of prematurity [Pro-oksidansi i antioksidansi u prematurnoj retinopatiji]
(Sestre Milosrdnice Univ Hospital, Zagreb, 2018)
Premature infants are susceptible to oxidative stress that causes neonatal disease such as retinopathy of prematurity (ROP). Oxidative stress is an imbalance between the production of pro-oxidants and the ability of the ...