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The use of a response surface methodology on HPLC analysis of methyldopa, amiloride and hydrochlorothiazide in tablets
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
A multifactor optimisation technique is successfully applied to develop a new HPLC method in which methyldopa, hydrochlorothiazide and amiloride were analysed and determined on a C18 column with detection at 286 nm. The ...
A preliminary study of beta-cyclodextrin/metoprolol tartrate inclusion complex for potential enantiomeric separation
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
The inclusion complex formation between Metoprolol tartarata (MeT) and beta -cyclodextrin (beta -CD) has been investigated using hyperchromic shift at lambda (max) 274.4 nm of MeT. Different parameters such as stirring ...
Simultaneous HPLC determination of nitrendipine and impurities of the process of synthesis
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
A method has been developed for separation of nitrendipine and its impurities of reaction partners and side reaction products by high-performance liquid chromatographic method on a RP-ls column and detection at 238 nm. The ...
Quantitative analysis of analgoantipyretics in dosage form using planar chromatography
(Pergamon-Elsevier Science Ltd, Oxford, 2001)
In the therapy of pain of weaker genesis, frequently used drugs usually represent a mix of analgoantipyretics of different chemical structures, mostly derivatives of salicylic acid, pyrazolone and p-aminophenol as well as ...