Претраживање
Приказ резултата 1-10 од 71
Greener chemistry in analytical sciences: from green solvents to applications in complex matrices. Current challenges and future perspectives: a critical review
(Royal Society of Chemistry, 2023)
More environment-friendly solvents in analytical chemistry are almost inevitable in both sample preparation and analysis to meet the high standards of sustainable chemistry and human welfare. In this review paper, a critical ...
High amount of lecithin facilitates oral delivery of a poorly soluble pyrazoloquinolinone ligand formulated in lipid nanoparticles: Physicochemical, structural and pharmacokinetic performances
(Elsevier B.V., 2023)
Preclinical development of deuterated pyrazoloquinolinone ligands, promising drug candidates for various neuropsychiatric disorders, was hindered by unusually low solubility in water and oils. DK-I-60-3 (7-methoxy-d3- ...
Encapsulation of cannabidiol in oil-in-water nanoemulsions and nanoemulsion-filled hydrogels: A structure and biological assessment study
(Academic Press Inc., 2023)
Hypothesis: Lipophilic cannabidiol can be solubilized in oil-in water nanoemulsions, which can then be impregnated into chitosan hydrogels forming another colloidal system that will facilitate cannabidiol's release. The ...
SIRT2i_Predictor: A Machine Learning-Based Tool to Facilitate the Discovery of Novel SIRT2 Inhibitors
(MDPI, 2023)
A growing body of preclinical evidence recognized selective sirtuin 2 (SIRT2) inhibitors as novel therapeutics for treatment of age-related diseases. However, none of the SIRT2 inhibitors have reached clinical trials yet. ...
Approximate treatment of noncommutative curvature in quartic matrix model
(Springer Science and Business Media Deutschland GmbH, 2023)
We study a Hermitian matrix model with the standard quartic potential amended by a tr(RΦ2) term for fixed external matrix R. This is motivated by a curvature term in the truncated Heisenberg algebra formulation of the ...
Application of Machine-Learning Algorithms for Better Understanding the Properties of Liquisolid Systems Prepared with Three Mesoporous Silica Based Carriers
(MDPI, 2023)
The processing of liquisolid systems (LSS), which are considered a promising approach
to improving the oral bioavailability of poorly soluble drugs, has proven challenging due to the
relatively high amount of liquid phase ...
Health Risk in a Geographic Area of Thailand with Endemic Cadmium Contamination: Focus on Albuminuria
(MDPI, 2023)
An increased level of cadmium (Cd) in food crops, especially rice is concerning because rice is a staple food for over half of the world’s population. In some regions, rice contributes to more than 50% of the total Cd ...
Revalorization of Cotton and Cotton/Elastane Knitted Fabric Waste
(Springer, 2023)
The present paper demonstrates a simple way for revalorization of differently softened cotton and cotton/elastane knitted fabric waste collected from the textile industry. Such waste was used as an adsorbent for Congo Red ...
Carbonization of MOF-5/Polyaniline Composites to N,O-Doped Carbon/ZnO/ZnS and N,O-Doped Carbon/ZnO Composites with High Specific Capacitance, Specific Surface Area and Electrical Conductivity
(MDPI, 2023)
Composites of carbons with metal oxides and metal sulfides have attracted a lot of interest as materials for energy conversion and storage applications. Herein, we report on novel N,O-doped carbon/ZnO/ZnS and N,O-doped ...
In-Depth Analysis of Physiologically Based Pharmacokinetic (PBPK) Modeling Utilization in Different Application Fields Using Text Mining Tools
(MDPI, 2023)
In the past decade, only a small number of papers have elaborated on the application of physiologically based pharmacokinetic (PBPK) modeling across different areas. In this review, an in-depth analysis of the distribution ...