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Приказ резултата 11-20 од 1393
Curcumin Nanonization Using An Alternative Small-Scale Production Unit: Selection of Proper Stabilizer Applying Basic Physicochemical Consideration and Biological Activity Assessment of Nanocrystals
(Walter de Gruyter GmbH, 2020)
As the number of poorly soluble drugs is increasing, nanocrystals have become very interesting due to wide range of application possibilities. Curcuminwas used as a model active ingredient in this work. Even though it has ...
Chitosan/Sodium Dodecyl Sulfate Complexes for Microencapsulation of Vitamin E and Its Release Profile— Understanding the Effect of Anionic Surfactant
(MDPI, 2021)
Microencapsulation of bioactive substances is a common strategy for their protection and release rate control. The use of chitosan (Ch) is particularly promising due to its abundance, biocompatibility, and interaction with ...
Optimization of the lyophilisation process for esomeprazole 40 mg powder for solution for injection/infusion using quality by design concept
(Elsevier, 2022)
The aim of this work was to apply the of Quality by Design concept in optimization of lyophilisation process in production of esomeprazole 40 mg powder for solution for injection/infusion. Optimization has been triggered ...
Bcs class iv oral drugs and absorption windows: Regional-dependent intestinal permeability of furosemide
(MDPI AG, 2020)
Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class. While solubility is often ...
H2FPEF score predicts atherosclerosis presence in patients with systemic connective tissue disease
(Wiley Periodicals, 2021)
Background: Cardiovascular diseases are common cause of morbidity and mortality in patients with systemic connective tissue diseases (SCTD) due to accelerated atherosclerosis which couldn't be explained by traditional risk ...
Synthesis and characterization of copper(II) octaazamacrocyclic complexes with glycine derivatives. In vitro antiproliferative and antimicrobial evaluation of the Cu(II) and Co(II) analogous
(Belgrade : Serbian Chemical Society, 2020)
Two new complexes with the general formula [Cu2(L)tpmc](ClO4)3·nH2O (tpmc = N,N′,N′′,N′′′-tetrakis(2-pyridylmethyl)- -1,4,8,11-tetraazacyclotetradecane, L = N-methylglycine, n = 3; L = N,N- -dimethylglycine, ...
Current computer-aided drug design methodologies in discovery of novel drug candidates for neuropsychiatric and inflammatory diseases / Metode kompjuterski potpomognutog dizajniranja lekova u istraživanju novih potencijalnih terapeutika za neuropsihijatrijske i inflamatorne bolesti
(Beograd : Savez farmaceutskih udruženja Srbije, 2021)
Drug discovery and development is a very challenging, expensive and time-consuming
process. Impressive technological advances in computer sciences and molecular biology have
made it possible to use computer-aided drug ...
Towards optimal ph of the skin and topical formulations: From the current state of the art to tailored products
(MDPI AG, 2021)
Acidic pH of the skin surface has been recognized as a regulating factor for the maintenance of the stratum corneum homeostasis and barrier permeability. The most important functions of acidic pH seem to be related to the ...
Shotgun metagenomics reveals differences in antibiotic resistance genes among bacterial communities in Western Balkans glacial lakes sediments
(NLM (Medline), 2020)
Long-term overuse of antibiotics has driven the propagation and spreading of antibiotic resistance genes (ARGs) such as efflux pumps in the environment, which can be transferred to clinically relevant pathogens. This study ...
What role does carbonized tannic acid play in energy storage composites?
(Elsevier Ltd, 2022)
Transformation of tannic acid (TA), a cheap, abundant and environmentally friendly (by)product, upon carbonization at various temperatures was examined as it is extensively being used in energy storing devices. In addition ...