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Computer-aided biopharmaceutical characterization: Gastrointestinal absorption simulation
(Elsevier Inc., 2013)
This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input ...
Artificial neural networks in the optimization of microemulsion liquid chromatography retention and resolution
(Nova Science Publishers, Inc., 2011)
Artificial neural networks (ANNs) present a powerful tool for the modeling of chromatographic retention and resolution as they provide the ability to predict the effects of changes in chosen chromatographic parameters under ...
Experimental design application interpretation in pharmaceutical technology
(Elsevier Inc., 2013)
This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett-Burman design, ...
The antioxidant role of ferritin and transferrin in elite athletes
(Nova Science Publishers, Inc., 2012)
Physical activity has been shown to increase the production of free radicals to a point that can exceed internal protective antioxidant system. The harmful effects of free radicals are neutralized by activity of antioxidant ...
Properties and biomedical relevance of phytosome encapsulated polyphenolics
(Nova Science Publisher Inc., 2017)
Polyphenols are secondary metabolites of plants, containing in their structure the aromatic ring with one or more phenolic groups. Such molecules have great antioxidant potential. They can modulate the activity of many ...
Natural and Modified Silica-Based Materials as Carriers for NSAIDs
(Elsevier Inc., 2017)
In the last two decades several representatives of natural silica-based materials (clays, zeolites, and diatomites) have emerged in biomedical applications due to their favorable physicochemical and functionality-related ...
Percutaneous penetration enhancement potential of microemulsion-based organogels
(Springer Berlin Heidelberg, 2016)
The skin, and particularly the most outer layer stratum corneum, is an effective barrier for molecules administered by conventional topical formulations (i.e., ointments, creams, hydrogels). Therefore, vehicles and carriers ...
Alkyl Polyglucoside-based delivery systems: In vitro/in vivo skin absorption assessment
(Elsevier Inc., 2014)
Skin permeation and penetration assessment is important not only for determining efficacy of a topical product, but also when comparing different formulations during development. This chapter reviews methods for dermal ...
Polymeric Microparticles and Inorganic Micro/Nanoparticulate Drug Carriers: An Overview and Pharmaceutical Application
(Elsevier Inc., 2017)
Recent expansion of innovative micro- and nanosized drug carriers has been driven by utilization of materials with improved functional properties, along with employment of innovative preparation techniques. Various materials ...
Biomedical application of fullerenes
(Nova Science Publishers, Inc., 2014)
The unique physical, chemical and biological properties of fullerenes have opened an intensive research on their possible applications in nanomedicine in the last few decades. The highly unsaturated structure of the ...