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Are moclobemide trough concentrations an adequate predictor of the systemic drug exposure
(Elsevier Science BV, Amsterdam, 2008)
Chiral catalysts in the stereoselective synthesis of pyrrolidine derivatives via metallo-azomethine ylides
(Pergamon-Elsevier Science Ltd, Oxford, 2005)
Ring closing metathesis/fragmentation route to (Z)-configured medium ring cycloalkenes. Total synthesis of (+/-)-periplanone C
(Amer Chemical Soc, Washington, 2006)
The combination of ring closing metathesis and beta-fragmentation offers an efficient entry into (Z)-configured medium ring cycloalkenes. The fragmentation step can be effected under anionic or radical conditions. The ...
High-performance liquid chromatographic method for the determination of moclobemide and its two major metabolites in human plasma
(Elsevier Science BV, Amsterdam, 2007)
A selective, sensitive, and simple high-performance liquid chromatographic (HPLC) method was developed for the determination of moclobemide and its two major metabolites, Ro 12-5637 and Ro 12-8095, in human plasma. Sample ...
Mixture design evaluation of drug release from matrix tablets containing carbomer and HPMC
(Elsevier Science BV, Amsterdam, 2006)
Isocratic RP-HPLC method for rutin determination in solid oral dosage forms
(Pergamon-Elsevier Science Ltd, Oxford, 2007)
A rapid and sensitive assay for quantitative determination of rutin in oral dosage forms based on isocratic reversed phase high performance liquid chromatography (RP-HPLC) was developed and validated. Using a C-18 reverse-phase ...
The antinociceptive effect of oxcarbazepine in a rat model of inflammatory hyperalgesia
(Elsevier Science BV, Amsterdam, 2004)
Premature centromere division of the X chromosome in neurons in Alzheimer's disease
(Wiley-Blackwell, Malden, 2008)
Premature centromere division (PCD) represents a loss of control over the sequential separation and segregation of chromosome centromeres. Although first described in aging women, PCD on the X chromosome (PCD,X) is markedly ...
Reversed-phase liquid chromatography analysis of imatinib mesylate and impurity product in Glivec (R) capsules
(Elsevier Science BV, Amsterdam, 2004)
The reversed-phase high-performance liquid chromatographic (RP-HPLC) method has been developed and validated for the simultaneous determination of imatinib mesylate and of the impurity product in Glivec(R) capsules (Novartis, ...
Nitric oxide in diquat neurotoxicity
(Elsevier Ireland Ltd, Clare, 2006)