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Quinazoline-based analog of adenine as an antidote against MLL-rearranged leukemia cells: synthesis, inhibition assays and docking studies
(Newlands Press, 2022)
Post-translational modifications of histones constitute a dynamic process impacting gene expression. A well-studied modification is lysine methylation. Among the lysine histone methyltransferases, DOT1L is implicated in ...
Positive modulation of α5GABAA receptors leads to dichotomous effects in rats on memory pattern and GABRA5 expression in prefrontal cortex and hippocampus
(Elsevier B.V., 2022)
Positive allosteric modulators (PAMs) of α5GABAA receptors (α5GABAARs) are emerging as potential therapeutics for a range of neuropsychiatric disorders. However, their role in memory processing of healthy animals is not ...
New azamacrocyclic binuclear Cu(II) aminocarboxylate complexes: Structural, magnetic, spectral and antiproliferative studies
(Elsevier B.V., 2022)
New cationic complexes of Cu(II) with bridged aminocarboxylates: glycine and alanine, as well as octaazamacrocyclic ligand N,N',N'',N'''-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane (tpmc), with general ...
Microwave Assisted Esterification of Aryl/Alkyl Acids Catalyzed by N-Fluorobenzenesulfonimide
(MDPI, 2022)
The susceptibility of the carbonyl group towards nucleophilic attack affords the construction of various organic compounds. Thus, investigations of carbonyl activation applying greener methodologies are highly important. ...
Binuclear Co(II) complexes with macrocycle and carboxylato ligands: structure, cytotoxicity and thermal behavior
(Elsevier B.V., 2021)
In vitro cytotoxic evaluation, formation constants and thermal stability of four mixed-ligand Co(II) complexes with tpmc = N,N',N",N'"-tetrakis(2-pyridylmethyl)-1,4,8,11-tetraazacyclotetradecane and carboxylate/dicarboxylate ...
C-protein α-antigen modulates the lantibiotic thusin resistance in Streptococcus agalactiae
(Springer Nature, 2021)
Screening for producers of potent antimicrobial peptides, resulted in the isolation of Bacillus cereus BGNM1 with strong antimicrobial activity against Listeria monocytogenes. Genome sequence analysis revealed that BGNM1 ...
The Applications of New Inorganic Polymer for Adsorption Cadmium from Waste Water
(Springer Nature, 2020)
Fundamental research of inorganic polymers prepared from available aluminosilicate precursors represent an innovative class of materials characterized by low energy consumption for production. This is just one of the reasons ...
Highly exo selective, photochemically promoted cyclization of iodoallene derivatives
(Wiley Periodicals LLC, 2022)
A photochemically promoted intramolecular cyclization of aryl-, vinyl-, and alkyliodo allenes has been developed. The optimal conditions employed [Ir(ppy)2(dtbbpy)]PF6 (1 mol%) as catalyst affording products with high exo ...
The Influences of Climatic and Lithological Factors on Weathering of Sediments in Humid Badland Areas
(Frontiers Media S.A., 2022)
Climate variables including temperature, rainfall intensity, rainfall acidity, and lithological properties are among the most important factors affecting rock weathering. However, the relative contribution of these four ...
Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL
(MDPI, 2022)
Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing ...