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Unexpected effect of dry olive leaf extract on the level of DNA damage in lymphocytes of lead intoxicated workers, before and after CaNa(2)EDTA chelation therapy
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
The CaNa(2)EDTA chelation therapy is often practiced with antioxidant supplementation. Dry olive leaf extract (DOLE) is natural product with antioxidant and DNA protective properties. The effects of DOLE on the levels of ...
Effects of short- and long-term physical activity on DNA stability and oxidative stress status in young soccer players
(Edizioni Minerva Medica, Turin, 2014)
Aim. The aim of the study was to determine whether single soccer training is able to cause oxidative stress and DNA instability. We have also sought to investigate if adaptive response will be developed during 45 days ...
Polychlorinated biphenyls as oxidative stress inducers in liver of subacutely exposed rats: Implication for dose-dependence toxicity and benchmark dose concept
(Academic Press Inc Elsevier Science, San Diego, 2015)
Hepatotoxicity is one of the well-documented adverse health effects of polychlorinated biphenyls (PCBs)persistent organic pollutants widely present in the environment. Although previous studies suggest possible role of ...
Paraoxonase activity in athletes with depleted iron stores and iron-deficient erythropoiesis
(Pergamon-Elsevier Science Ltd, Oxford, 2010)
Objective: The aim of this study was to evaluate how conditions that precede anaemia (iron store depletion and iron-deficient erythropoiesis) affect human serum paraoxonase PON1 activity. Design and methods: Based on ...
Insight into the oxidative stress induced by lead and/or cadmium in blood, liver and kidneys
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Besides being important occupational hazards, lead and cadmium are nowadays metals of great environmental concern. Both metals, without any physiological functions, can induce serious adverse health effects in various ...
Oxidative stress and paraoxonase 1 status in acute ischemic stroke patients
(Elsevier Ireland Ltd, Clare, 2015)
Objective: The connection of oxidative stress with dyslipidemia creates a newly-emerging atherosclerosis risk factor involved in acute ischemic stroke development. This study analyzed the influence of oxidative stress on ...
Evaluation of cytogenetic and DNA damage in human lymphocytes treated with adrenaline in vitro
(Pergamon-Elsevier Science Ltd, Oxford, 2015)
Catechol groups can be involved in redox cycling accompanied by generation of reactive oxygen species (ROS) which may lead to oxidative damage of cellular macromolecules including DNA. The objective of this investigation ...
Increased oxidative stress and cytokinesis-block micronucleus cytome assay parameters in pregnant women with gestational diabetes mellitus and gestational arterial hypertension
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
We investigated whether gestational diabetes mellitus (GDM) and gestational arterial hypertension (GH) are associated with increased oxidative stress and DNA damage. Study included 3 groups of pregnant women (GDM, GH and ...
Association of paraoxonase 1 and oxidative stress with acute kidney injury in premature asphyxiated neonates
(Elsevier Ireland Ltd, Clare, 2017)
Objectives: Acute kidney injury (AKI) is defined as a decrease in glomerular filtration rate with an increase in serum creatinine (sCr). Perinatal asphyxia (PNA) may be etiological factor for AKI with oxidative stress also ...
The usefulness of advanced lipid and oxidative stress testing for diagnosis and management of low HDL-cholesterol phenotype: A case report
(Pergamon-Elsevier Science Ltd, Oxford, 2017)
Objective: Plasma high-density lipoprotein cholesterol (HDL-C) level is a strong inverse predictor of cardiovascular disease (CVD) development. Tangier disease, a consequence of mutations in the ATP binding cassette ...