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TLC determination of glimepiride and its main impurities in pharmaceuticals
(Taylor & Francis Inc, Philadelphia, 2013)
A quantitative TLC method was developed for the simultaneous separation and quantification of glimepiride and its main degradation impurities, glimepiride-sulfonamide, and glimepiride-carbamate. Chromatographic analysis ...
Densitometric determination of omeprazole, pantoprazole, and their impurities in pharmaceuticals
(Research Inst Medicinal Plants, Budakalasz, 2004)
A method has been developed for separation of omeprazole and pantoprazole, and their impurities omeprazole sulfone and N-methylpantoprazole, by HPTLC. The mobile phase chloroform-2-propanol-25% ammonia-acetonitrile, 10.8 ...
Determination of Moxonidine and Its Impurities by Thin-Layer Chromatography
(Taylor & Francis Inc, Philadelphia, 2015)
A thin-layer chromatographic method for simultaneous determination of moxonidine and its four impurities was developed and validated. Separation of the examined compounds was performed on chromatographic plates precoated ...
Chromatographic determination of dissociation constants of pramipexole and its impurities
(Vieweg, Wiesbaden, 2007)
The main goal in this investigation was monocratic HPLC determination of dissociation constant values (pK(a)) of pramipexole and its impurities, BI-II 546 CL, BI-II 751 xx and 2-aminobenzothiazole. The chromatographic ...
Methylprednisolone and its related substances in freeze-dried powders for injections / Metilprednizolon i njegove srodne supstance u liofilizatu za rastvor za injekcije
(Srpsko hemijsko društvo, Beograd, 2010)
In this work, the behavior of the active pharmaceutical substances methylprednisolone (in a form of methylprednisolone sodium succinate) in finished pharmaceutical dosage form, i.e., freeze-dried powder for injections, was ...
A chemometrical approach to optimization and validation of an HPLC assay for rizatriptan and its impurities in tablets
(Taylor & Francis Inc, Philadelphia, 2007)
An isocratic reversed-phase high-performance liquid chromatographic method was developed and validated for the analysis of a novel antimigraine drug, rizatriptan benzoate, in a dosage form along with its two impurities, ...
Validation of an HPLC method for determination of aripiprazole and its impurities in pharmaceuticals
(Akademiai Kiado Rt, Budapest, 2014)
Aripiprazole is a novel atypical antipsychotic drug used in the treatment of schizophrenia. The sensitive and reproducible ion pair RPLC method was developed and validated for determination of aripiprazole and its nine ...
Monitoring of impurity level of valsartan and hydrochlorothiazide employing an RP-HPLC gradient mode
(Taylor & Francis Inc, Philadelphia, 2007)
The multi-component preparation Co -Diovan (R) is indicated for the hypertension treatment in patients whose blood pressure is not adequately controlled by monotherapy. Its active ingredients are valsartan and hydrochlorothiazide. ...
TLC determination of tiapride hydrochloride and its impurities in pharmaceuticals
(Taylor & Francis Inc, Philadelphia, 2012)
A simple and sensitive HPTLC method for separation and determination of tiapride hydrochloride and its degradation products has been developed and evaluated. Analysis of tiapride hydrochloride and impurities III, VII, and ...
TLC determination of glimepiride and its main impurities in pharmaceuticals
(Taylor & Francis Inc, Philadelphia, 2013)
A quantitative TLC method was developed for the simultaneous separation and quantification of glimepiride and its main degradation impurities, glimepiride-sulfonamide, and glimepiride-carbamate. Chromatographic analysis ...