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Spectroscopic studies on the drug–drug interaction: the influence of fluoroquinolones on the affinity of tigecycline to human serum albumin and identification of the binding site
(Springer, 2020)
bstract: Concomitant use of two or more drugs in therapy is becoming a more frequent phenomenon and clinically relevant drug–drug interactions at the level of binding to human serum albumin (HSA) are more often. The influence ...
Discovery of membrane permeability, pharmacokinetics properties and mechanism of action for analogs of ethylenediamine-n,n′-di-2-(3-cyclohexyl)propionic acid and 1,3-propandiamine-n,n′-di-2-(3-cyclohexyl)propionic acid with antiproliferative activity using In Vitro and In Silico Methods
(Springer Verlag, 2020)
In previously in vitro studies on different cell lines and in vivo on melanoma and 4T1 murine breast cancer and metastasis it was shown antiproliferative activity for ester derivatives of (S,S)-ethylenediamine-N,N′-di-2- ...
Sex as a confounding factor in the effects of ageing on rat lymph node t cell compartment
(Elsevier Inc., 2020)
The study examined the influence of sex on the alterations occurring with ageing in rat lymph node (LN) T cell compartment. In female and male rats the decrease in LN T cell counts was followed by a shift in CD4+/CD8+ T ...
Phenotypic and genetic properties of susceptible and multidrug-resistant Pseudomonas aeruginosa isolates in Southern Serbia / Fenotipska i genetička obilježja osjetljivih i višestruko otpornih izolata Pseudomonas aeruginosa u južnoj Srbiji
(Sciendo, 2020)
Drug resistance of Pseudomonas aeruginosa is a leading problem in hospital infections. The aim of this study was to determine the best molecular genetic discrimination method for Pseudomonas spp. isolates among 94 outpatients ...
COVID-19 Vaccines Safety Tracking (CoVaST): Protocol of a Multi-Center Prospective Cohort Study for Active Surveillance of COVID-19 Vaccines’ Side Effects
(MDPI, 2021)
Background: Coronavirus disease (COVID-19) vaccine-related side effects have a determinant role in the public decision regarding vaccination. Therefore, this study has been designed to actively monitor the safety and ...
The evaluation of the effect of different superdisintegrants on the drug release from FDM 3D printed tablets through different applied strategies: In vitro-in silico assessment
(Elsevier B.V., 2021)
Paracetamol-loaded tablets were printed by fused deposition modelling technique, using polyvinyl alcohol as a backbone polymer and Affinisol™ HPMC as a plasticizer in all formulations. Four different strategies were applied ...
Influence of surface coverage of kaolin with surfactant ions on adsorption of ochratoxin A and zearalenone
(Elsevier Ltd, 2021)
A natural kaolin from Serbia was modified with different amounts of octadecyldimethylbenzyl ammonium (ODMBA) - (25, 50 and 90% of kaolin cation exchange capacity). Samples were denoted as OKR-25, OKR-50 and OKR-90. Several ...
Design and characterization of a novel structural class of Kv1.3 inhibitors
(Elsevier, 2020)
The voltage-gated potassium channel Kv1.3 is involved in multiple autoimmune diseases, such as multiple sclerosis, rheumatoid arthritis, diabetes mellitus type 1 and psoriasis. In many auto-immune diseases better treatment ...
Effect of urine adulterants on commercial drug abuse screening test strip results / Utjecaj adulteranata u mokraći na nalaze komercijalnih testnih traka za otkrivanje zloporabe droga
(Sciendo, 2020)
Immunochromatographic strips for urine drug screening tests (UDSTs) are common and very suitable for drug abuse monitoring, but are also highly susceptible to adulterants kept in the household, which can significantly alter ...
Локално периферно аналгетичко дејство метформина у моделу инфламаторног бола – учешће серотонинских 5-HT1A и 5-HT1B/1D рецептора / The local peripheral analgesic effect of metformin in a model of inflammatory pain – role of serotonin 5-HT1A and 5-HT1B/1D receptors
(2022)
Метформин је широко употребљивани антидијабетик. Показано је да системски примењен метформин испољава антиноцицептивни ефекат у који су укључени одређени серотонински рецептори.