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Приказ резултата 1-10 од 901
Novel Pharmaceutical and Nutraceutical-Based Approaches for Cardiovascular Diseases Prevention Targeting Atherogenic Small Dense LDL
(MDPI, 2022)
Compelling evidence supports the causative link between increased levels of low-density lipoprotein cholesterol (LDL-C) and atherosclerotic cardiovascular disease (CVD) development. For that reason, the principal aim of ...
Expanding the Accessible Chemical Space of SIRT2 Inhibitors through Exploration of Binding Pocket Dynamics
(American Chemical Society, 2022)
Considerations of binding pocket dynamics are one of the crucial aspects of the rational design of binders. Identification of alternative conformational states or cryptic subpockets could lead to the discovery of completely ...
Performance comparison of nonlinear and linear regression algorithms coupled with different attribute selection methods for quantitative structure - retention relationships modelling in micellar liquid chromatography
(Elsevier, 2020)
In micellar liquid chromatography (MLC), the addition of a surfactant to the mobile phase in excess is accompanied by an alteration of its solubilising capacity and a change in the stationary phase’s properties. As an ...
Body mass index is independently associated with xanthine oxidase activity in overweight/obese population
(Springer International Publishing, 2020)
Purpose: The pathophysiological mechanism of the relationship between xanthine oxidase (XO) activity and obesity has not been completely elucidated. Since inflammation and oxidative stress are regarded as key determinants ...
Antioxidant capacity and antimicrobial effects of zinc complexes of flavonoids – does synergism exist? / Aнтиоксидативен капацитет и антимикробни ефекти на комплекси на цинк со флавоноиди – дали постои синергизам?
(Macedonian Journal of Chemistry and Chemical Engineering, 2021)
The presence of residual cardiovascular disease (CVD) risk is a current dilemma in clinical practice; indeed, despite optimal management and treatment, a considerable proportion of patients still undergo major CV events. ...
Gelation behavior, drug solubilization capacity and release kinetics of poloxamer 407 aqueous solutions: The combined effect of copolymer, cosolvent and hydrophobic drug
(Elsevier B.V., 2020)
The study elucidated the combined effect of the formulation parameters (the relative contents of the copolymer (poloxamer 407 (P407)), the cosolvent (isopropyl alcohol), and the hydrophobic drug (ibuprofen)) on gelation, ...
Curcumin-loaded low-energy nanoemulsions: Linking EPR spectroscopy-analysed microstructure and antioxidant potential with in vitro evaluated biological activity
(Elsevier B.V., 2020)
The objective of this work was to investigate and profoundly characterize low-energy nanoemulsions as multifunctional carriers, with slight reference to dermal administration. An evidence-based approach was offered for ...
Charged aerosol detector response modeling for fatty acids based on experimental settings and molecular features: a machine learning approach
(BioMed Central Ltd, 2021)
The charged aerosol detector (CAD) is the latest representative of aerosol-based detectors that generate a response independent of the analytes’ chemical structure. This study was aimed at accurately predicting the CAD ...
Diversification of yellow-flowered Sempervivum (Crassulaceae) species from the Balkan Peninsula: evidence from the morphometric study of the epidermal structures of rosette leaves / Različitost žutocvetnih vrsta roda Sempervivum (Crassulaceae) Balkanskog poluostrva: rezultati morfometrijskog istraživanja epidermalnih struktura listova rozete.
(Institute of Botany and Botanical Garden "Jevremovac", University of Belgrade, 2021)
Several related yellow-flowered houseleek species which occur on the Balkan Peninsula are divided into two complexes: Sempervivum ciliosum (S. ciliosum, S. jakucsii, S. klepa, S. octopodes, and S. galicicum) and the S. ...
Phosphatidylserine Exposing Extracellular Vesicles in Pre-eclamptic Patients
(Frontiers Media S.A., 2021)
Background: Pre-eclampsia (P-EC) is associated with systemic inflammation, endothelial dysfunction and hypercoagulability. The role of extracellular vesicles (EVs) in coagulation disturbances affecting the development and ...