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Development of Karl Fischer titration method using Duality by Design concept / Razvoj metode titracije po Karl Fišeru primenom tzv. Quality by Design koncepta
(Savez hemijskih inženjera, Beograd, 2012)
Modern trends in drug quality control are moving toward incorporating quality into the method during its development. That course is in accordance with Quality by Design (QbD) concept defined by ICH Q 8 (R2) guideline. ...
Toxicity mechanisms and interactions of polychlorinated biphenyls and polybrominated diphenylethers / Mehanizmi toksičnog dejstva i interakcije polihlorovanih bifenila i polibromovanih difenil etara
(Univerzitet u Beogradu - Fakultet veterinarske medicine, Beograd, 2012)
Polychlorinated biphenyls (PCBs) and brominated flame retardants, polybrominated diphenylethers (PBDEs), are widespread environmental contaminants as a result of anthropogenic activities and due to their persistency and ...
The effect of pre-treatment with l-name on glutathione and glutathione peroxidase in parquat-induced neurotoxicity in rat striatum / Efekat predtretmana sa l-name na glutation i glutation peroksidazu u strijatumu pacova na neurotoksičnost izazvanu parakvatom
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Contact herbicide paraquat (DQ) is bipyridylium compound, which undergoes redox metabolism; hence enlarged in humans radical production mediated its toxicity. Target organs of systemic effect of PQ poisoning are lung and ...
Purification of biological samples and validation of bioanalytical HPLC methods for analysis of drugs and their metabolites / Priprema biološkog materijala i validacija bioanalitičkih HPLC metoda za ispitivanje lekova i njihovih metabolite
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Purification of biological matrix prior to HPLC analysis has been complex procedure and source of great variability of analytical results. The most used biological matrixes used for analysis are plasma, serum, urine and ...
Mechanistic simulation of carbamazepine absorption after oral administration of immediate release tablets / In silico predviđanje apsorpcije karbamazepina nakon oralne primene tableta sa trenutnim oslobađanjem
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The main prerequisite to establish quantitative in vitro-in vivo correlation (IVIVC) and define biorelevant in vitro methodology is to identify drug dissolution profile in vivo. When intravenous data are not available due ...
Psychoactive controlled substances: Current situation in the world / O psihoaktivnim kontrolisanim supstancama - situacija u svetu
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Although the psychoactive substances are strictly controlled in most of the countries in the world, their abuse is still very present, as confirmed by the data from the year of 2009 when over 200 million drug addicts were ...
Adverse effects and toxicity of analgesics / Neželjeni efekti i toksičnost analgetika
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Even though among the most widely used analgoantipiretics with confirmed pharmacological effects, acetylsalicylic acid, paracetamol and ibuprofen may be the cause of poisonings and even death. Acetylsalicylic acid and ...
Development and validation of a fluorometric method for the determination of hesperidin in human plasma and pharmaceutical forms / Razvoj i validacija fluorimetrijske metode za određivanje hesperidina u humanom serumu i farmaceutskim preparatima
(Srpsko hemijsko društvo, Beograd, 2012)
A fluorometric method, based on the fluorescence properties of the aluminium(III)-hesperidin complex, for the determination of hesperidin in human plasma and pharmaceutical forms has been developed and validated. The complex ...
A PAMPA Assay as Fast Predictive Model of Passive Human Skin Permeability of New Synthesized Corticosteroid C-21 Esters
(MDPI, Basel, 2012)
The permeation properties of twenty newly synthesized alpha-alkoxyalkanoyl and alpha-aryloxyalkanoyl C-21 esters of standard corticosteroids: Fluocinolone acetonide, dexamethasone, triamcinolone acetonide and hydrocortisone ...
Adiponectin, non-esterified fatty acids and antiphospholipid antibodies in type II diabetes mellitus
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2012)
The importance of the association of antiphospholipid antibodies (aPL Abs) with the features of type II diabetes mellitus has not yet been elucidated. The aim of this work was to investigate the association of aPL Abs with ...