Претраживање
Приказ резултата 101-106 од 106
In vitro study of redox properties of azolyl-lactones in human serum / In vitro студија редокс особина азолил-лактона у хуманом серуму
(Serbian Chemical Society, 2023)
Disruption of the redox balance in the body causes oxidative stress that can initiate many diseases. While antioxidants reduce the level of oxidiz- ing compounds in the medium, prooxidants promote the opposite process and ...
Protein degradation induced by PROTAC molecules as an emerging drug discovery strategy / Деградација протеина индукована PROTAC молекулима као нова стратегија у развоју лекова
(Serbian Chemical Society, 2022)
The traditional concept of drug discovery is based on the occupancydriven pharmacology model. It implies the development of inhibitors occupying binding sites that directly affect protein functions. Therefore, proteins ...
The importance of the accuracy of the experimental data for the prediction of solubility / Važnost preciznosti eksperimentalnih podataka za procenu rastvorljivosti
(Srpsko hemijsko društvo, Beograd, 2010)
Aqueous solubility is an important factor influencing several aspects of the pharmacokinetic profile of a drug. Numerous publications present different methodologies for the development of reliable computational models for ...
Synthesis and biological profiling of novel isocoumarin derivatives and related compounds / СИНТЕЗА И БИОЛОШКО ПРОФИЛИСАЊЕ НОВИХ ИЗОКУМАРИНСКИХ ДЕРИВАТА И СЛИЧНИХ ЈЕДИЊЕЊА
(Serbian Chemical Society, 2021)
In the continuation of our study of substituted isocoumarins a series of novel 3-azolyl isocoumarin and their thio derivatives, including some related lactone compounds was prepared and biologically profiled against C. ...
Application of liquid chromatography in defining the interaction of newly synthesized chalcones and related compounds with human serum albumin / Примена течне хроматографије у дефинисању интеракција новосинтетисаних халкона и сродних супстанци са хуманим серумским албуминима
(Srpsko hemijsko društvo, Beograd, 2023)
Defining the interaction of newly synthesized compounds with plasma proteins is an important step in the drug development process. Chromatographic techniques can be successfully used in predicting the biopharmaceutical ...
The influence of different enzymatic preparations and skin contact time on aromatic profile of wines produced from autochthonous grape varieties Krstac and Zizak / Утицај различитих ензимских третмана и времена контакта покожице на ароматске профиле вина произведених од аутохтоних сорти грожђа Крстач и Жижак
(Serbian Chemical Society, 2023)
This study aimed to show aromatic profile of wines produced from two autochthonous grape cultivars Krstač (K) and Žižak (Z). During the wine production two enzymatic preparations (EP) Lallzyme cuvee blanc (CB) and Lallzyme ...