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Chronic alpha(1)-adrenoreceptor blockade produces age-dependent changes in rat thymus structure and thymocyte differentiation
(F Hernandez, Murcia, 2005)
In order to examine the influence of chronic alpha(1)-adrenergic receptor (alpha(1)-AR) blockade on the thymus structure and T-cell maturation, peripubertal and adult male rats were treated with urapidil (0.20 mg/kg BW/d; ...
Differential effects of chronic propranolol treatment on the phenotypic profile of thymocytes from immature and adult rats
(Elsevier Science BV, Amsterdam, 2000)
To elucidate a putative role of beta-adrenoceptors in the modulation of intrathymic T-cell maturation, the expression of major differentiational antigene (CD4/CD8 and TCR alpha beta) on the thymocytes from both immature ...
Interaction of quinapril anion with cationic surfactant micelles of cetyltrimethylammonium bromide
(Academic Press Inc Elsevier Science, San Diego, 2006)
In this study, the interaction of the anion of quinapril (QUIN), angiotensin converting enzyme (ACE) inhibitor, with cationic surfactant cetyltrimethylammonium bromide (CTAB) was investigated. The effect of cationic micelles ...
Effect of pentoxifylline on differentiation and maturation of human monocyte-derived dendritic cells in vitro
(Elsevier Science BV, Amsterdam, 2007)
Pentoxifylline (PTX) is a drug used for the treatment of vascular disorders, but it also has a positive therapeutic effect in experimental models of some autoimmune diseases. In this work, we studied the effect of PTX on ...
Cortisol response to ACTH stimulation correlates with blood interleukin 6 concentration in healthy humans
(Bioscientifica Ltd, Bristol, 2008)
Objective: Interleukin 6(IL6) has the ability to influence each level of the hypothalamo-pituitary-adrenocortical (HPA) axis. The aim of the study was to test whether IL6 concentration correlates with the adrenal cortex ...
Development of a HPTLC method for in-process purity testing of pentoxifylline
(Wiley-VCH Verlag GMBH, Weinheim, 2005)
A HPTLC method for the separation and identification of pentoxifylline and related substances, impurities of reaction partners, and side reaction products has been developed using different mobile and stationary phases. ...
Homocysteine serum levels and MTHFR C677T genotype in patients with Parkinson's disease, with and without levodopa therapy
(Elsevier Science BV, Amsterdam, 2006)
Both methylenetetrahydrofolate (MTHFR) C677T genotype and levodopa treatment may give rise to elevated serum homocysteine levels in parkinsonian patients. We aimed to clarify the interplay of these factors in pathogenesis ...
Chiral ligand-exchange chromatography for diastereo-enantio separation of exametazime
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
The diastereo-enantio separation of isomeric mixtures of exametazime (HM-PAO) by liquid chromatography is described using an achiral sorbent (RP-18). A chiral eluent with the initial complex of Cu(II) and the optically ...
The role of rat Crry, a complement regulatory protein, in proliferation of thymocytes
(Pergamon-Elsevier Science Ltd, Oxford, 2004)
In our previous work we showed that 3F10 monoclonal antibody (mAb), which recognizes the rat complement receptor 1-related/gene protein y (Crry), induces homotipic aggregation of thymocytes. In this work we studied the ...
Neonatal castration affects intrathymic kinetics of T-cell differentiation and the spleen T-cell level
(Bioscientifica Ltd, Bristol, 2007)
To test putative interdependence in the ontogenesis of the hypothalamic-pituitary-gonadal and thymic-lymphatic axes, thymocyte differentiation and maturation was examined in neonatally castrated (Cx) adult rats. In the ...