Pretraživanje
Prikaz rezultata 41-50 od 5472
In vitro/in silico approach in the development of simvastatin-loaded self-microemulsifying drug delivery systems
(Taylor & Francis Ltd, Abingdon, 2018)
Objective: The aims of this study were to formulate simvastatin (SV)-loaded self-microemulsifying drug delivery systems (SMEDDS), and explore the potential of these drug delivery systems to improve SV solubility, and also ...
Toxic elements in children's crayons and colored pencils: Bioaccessibility assessment / Tоксични елементи у воштаним и дрвеним бојицама за децу: процена биодоступности
(Serbian Chemical Society, 2022)
Crayons and colored pencils for children may contain toxic elements (TEs) exhibiting potential risk for children’s health including cognitive development, after their ingestion, through mouthing and chewing and eventually, ...
The Pharmacokinetics of Recombinant Human Erythropoietin in Balkan Endemic Nephropathy Patients
(Soc Espanola Nefrologia Dr Rafael Matesanz, Madrid, 2013)
Background: Balkan endemic nephropathy (BEN) hemodialysis patients require a higher dose of recombinant human erythropoietin for maintaining target hemoglobin level than patients with other kidney diseases. Objectives: ...
Polymer-stabilized emulsion systems: Structural characteristics and physical stability evaluation
(Taylor & Francis Ltd, Abingdon, 2003)
In the course of investigation of the effects of polymeric emulsifier (Simulgel(R)A) on the structural characteristics and physical stability (during storage time) of semisolid o/w emulsion systems with different emulsifier ...
Liquid chromatographic-mass spectrometric method for the determination of fluoxetine and norfluoxetine in human plasma: Application to clinical study
(Elsevier Masson SAS, 2005)
A selective, sensitive, simple, and rapid method for the simultaneous determination of fluoxetine (FL) and norfluoxetine (nor-FL) was developed and validated, and further applied to analyze plasma samples obtained from ...
Study on protolytic equilibria of lorazepam and oxazepam by UV and NMR spectroscopy
(Pergamon-Elsevier Science Ltd, Oxford, 2003)
Protolytic equilibria in homogeneous and heterogeneous systems of lorazepam and oxazepam, which are sparingly soluble ampholytes from the class of 1,4-benzodiazepines, were studied at 25 degreesC and ionic strength of 0.1 ...
Quantitative analysis of nimesulide in plasma by thin-layer chromatography: Application to pharmacokinetic studies in man
(Research Inst Medicinal Plants, Budakalasz, 2003)
A thin-layer chromatographic (TLC) method for quantitative analysis of nimesulide in human plasma has been developed, validated, and applied to a pharmacokinetic study of healthy volunteers. A previously published method ...
Determination of dissociation constants of quercetin
(Govi-Verlag Gmbh, Eschborn, 2003)
Procena učestalosti i prediktora klinički značajnih lek-lek interakcija i njihov uticaj na ishode terapije pacijenata sa kardiovaskularnim oboljenjima
(Универзитет у Београду, Фармацеутски факултет, 2020)
Lek-lek interakcije (LLI) su čest uzrok pojave neželjenih ishoda terapije kroz izmenu u efikasnosti ili bezbednosti terapije, a koji se može prevenirati. Posledice LLI nisu dovoljno istražene zbog njihovog neprepoznavanja. ...
Bcs class iv oral drugs and absorption windows: Regional-dependent intestinal permeability of furosemide
(MDPI AG, 2020)
Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class. While solubility is often ...