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Приказ резултата 21-30 од 1883
Development of a prospective isopropyl alcohol-loaded pharmaceutical base using simultaneous in vitro/in vivo characterization methods of skin performance
(Informa Healthcare, London, 2014)
Context: Approaching of pharmaceutical and cosmetic industries in some aspects inevitably influence formulation of topical pharmaceuticals, urging researchers to introduce novel excipients with proven benefits over traditional ...
Multi-Level Robustness Evaluation Approach: From Robustness Criterion to Adapted Algorithm of Dong
(Springer Heidelberg, Heidelberg, 2013)
This paper proposes an innovative concept for robustness evaluation guided by two crucial aims: indubitable identification of the factors that significantly affect the LC method and avoidance of unnecessary time and money ...
Development of a novel RP-HPLC method for the efficient separation of aripiprazole and its nine impurities
(Wiley-VCH Verlag GMBH, Weinheim, 2013)
The development of an RP-HPLC method for the separation of aripiprazole and its nine impurities was performed with the use of partial least squares regression, response surface plot methodology, and chromatographic response ...
Stress Degradation Studies on Zolpidem Tartrate Using LC-DAD and LC-MS Methods
(Akademiai Kiado Zrt, Budapest, 2014)
The present study was designed to characterize the possible degradation products of zolpidem tartrate under various stress conditions according to International Conference on Harmonization (ICH) guidelines Q1A(R2). After ...
Two copies of bla (NDM-1) gene are present in NDM-1 producing Pseudomonas aeruginosa isolates from Serbia
(Springer, Dordrecht, 2014)
New Delhi metallo-beta-lactamase producing Pseudomonas aeruginosa isolates are of special interest since P. aeruginosa is a major cause of nosocomial infections, the treatment of which could now be jeopardized, especially ...
Treatment of Venous Ulcers with the Herbal-Based Ointment Herbadermal (R): A Prospective Non-Randomized Pilot Study
(Karger, Basel, 2012)
Background: Venous ulcers (ulcus cruris venosum) are a common chronic disease that requires continuing treatment and significantly influences a patient's way of life. The therapeutic effects of the ointment Herbadermal on ...
17 beta-carboxamide steroids - in vitro prediction of human skin permeability and retention using PAMPA technique
(Elsevier Science BV, Amsterdam, 2014)
In this paper, twenty-two 17 beta-carboxamide steroids were synthesized from five corticosteroids (hydrocortisone, prednisolone, methylprednisolone, dexamethasone and betamethasone) in two steps. The first step was periodic ...
Time-dependent changes of myeloperoxidase in relation to in-hospital mortality in patients with the first anterior ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention
(Pergamon-Elsevier Science Ltd, Oxford, 2012)
Objectives: To analyze the prognostic value of myeloperoxidase (MPO) in relation to in-hospital mortality and to identify the optimum time point for sampling in patients with the first anterior ST-segment elevation myocardial ...
Vigabatrin in dried plasma spots: Validation of a novel LC-MS/MS method and application to clinical practice
(Elsevier Science BV, Amsterdam, 2014)
This paper presents a LC-MS/MS method for the determination of antiepileptic drug vigabatrin in dried plasma spots (DPS). Due to its zwitterionic chemical structure, a pre-column derivatization procedure was performed, ...