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Influence of Promoter Polymorphisms of the Tnf-α (-308g/A) and IL-6 (-174g/C) Genes on Therapeutic Response to Etanercept in Rheumatoid Arthritis
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2015)
Background: The study was undertaken to assess the influence of functional -308G/A TNF-alpha (rs 1800629) and -174G/C IL-6 (rs1800795) promoter polymorphisms on the therapeutic response to etanercept, a TNF-alpha. blocker, ...
Plasma cathepsin S is associated with high-density lipoprotein cholesterol and bilirubin in patients with abdominal aortic aneurysms
(De Gruyter Open, 2019)
Cathepsin S (CTSS) is a cysteine protease involved in atherogenesis. We compared the plasma CTSS as well as other biomarkers of atherosclerosis in patients with abdominal aortic aneurysms (AAA) and aortoiliac occlusive ...
Nitric oxide products are not associated with metabolic syndrome
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2019)
Background: Nitric oxide (NO) is oxidative stress biomarker which is regarded as one of the key determinants of energy metabolism and vascular tone. Considering the controversial reports on the association between nitric ...
The clinical importance of biochemical bone markers in patients with alcoholic and viral liver cirrhosis
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2014)
Background: Metabolic bone disease in patients with chronic liver disease is called hepatic osteodystrophy and is primarily a sequel to osteopenia/osteoporosis, and rarely secondary to osteomalacia: The aim of this work ...
Women with Polycystic Ovary Syndrome and Risk of Cardiovascular Disease
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2017)
Background: Polycystic ovary syndrome (PCOS) is associated with reproductive and metabolic abnormalities. The aim of this study was to analyse risk of cardiovascular disease (CVD) in PCOS, to define individual risk factors ...
Medical Biochemistry as Subdiscipline of Laboratory Medicine in Serbia
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2017)
Medical biochemistry is the usual name for clinical biochemistry or clinical chemistry in Serbia, and medical biochemist is the official name for the clinical chemist (or clinical biochemist). This is the largest sub-discipline ...
Association of Myeloperoxidase and the Atherogenic Index of Plasma in Children with End-Stage Renal Disease
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2017)
Background: The aim of this study was to explore oxidative stress status, especially the enzyme myeloperoxidase in children with end-stage renal disease. Also, we investigated possible associations between the atherogenic ...
Introduction to Molecular genetic diagnostics
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2014)
Molecular genetic testing is part of modern medical practice. DNA tests are an essential part of diagnostics and genetic counseling in single gene diseases, while their application in polygenic disorders is still limited. ...
N-terminal pro-b-type natriuretic peptide in patients with hypertensive heart disease
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2011)
Patients with hypertensive heart disease have elevated concentrations of N-terminal pro-B-type natriuretic peptide (NT-proBNP). The aim of our study was to evaluate NT-proBNP in patients with long-standing hypertension and ...
Uncertainty of Measurement in Laboratory Medicine
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2018)
An adequate assessment of the measurement uncertainty in a laboratory medicine is one of the most important factors for a reliable interpretation of the results. A large number of standards and guidelines indicate the need ...