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Influence of Promoter Polymorphisms of the Tnf-α (-308g/A) and IL-6 (-174g/C) Genes on Therapeutic Response to Etanercept in Rheumatoid Arthritis
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2015)
Background: The study was undertaken to assess the influence of functional -308G/A TNF-alpha (rs 1800629) and -174G/C IL-6 (rs1800795) promoter polymorphisms on the therapeutic response to etanercept, a TNF-alpha. blocker, ...
Spectroscopic studies on the drug–drug interaction: the influence of fluoroquinolones on the affinity of tigecycline to human serum albumin and identification of the binding site
(Springer, 2020)
bstract: Concomitant use of two or more drugs in therapy is becoming a more frequent phenomenon and clinically relevant drug–drug interactions at the level of binding to human serum albumin (HSA) are more often. The influence ...
Apolipoprotein E polymorphism and severity of angiographically verified coronary artery disease
(Društvo medicinskih biohemičara Srbije i Crne Gore, Beograd i Univerzitet u Beogradu - Farmaceutski fakultet, Beograd, 1999)
Apolipoprotein E is an important genetic determinant of serum lipoprotein concentrations and coronary artery disease risk. The apo E polymorphism is a major determinant of interindividual variation in the initiation and ...
Evaluation of Diclofenac Sodium Release from Matrix Pellets Compressed into MUPS Tablets
(Pharmaceutical Soc Japan, Tokyo, 2009)
The purpose of the study was to screen the effects of formulation factors on the in vitro release profile of diclofenac sodium from matrix pellets compressed into multiple unit pellet system (MUPS) tablets using design of ...
Influence of ribavirin on the micronucleus formation and in vitro proliferation of human lymphocytes
(Slovak Academic Press Ltd, Bratislava, 2000)
Cytotoxic effects of the antiviremic drug ribavirin (1-beta -D-ribofuranosyl-1,2,4-triazole-3-carboxamide) were evaluated in vitro measuring micronucleus formation and cell proliferation kinetics in whole blood cultures ...
Fibre and polyphenols of selected fruits, nuts and green leafy vegetables used in Serbian diet
(Srpsko hemijsko društvo, Beograd, 2015)
Fruits and vegetables are known as good sources of numerous bioactive compounds among which polyphenols and dietary fibre are considered essential because of their protective health effects. The aim of this study was to ...
Imidazoline receptors ligands / Ligandi imidazolinskih receptora
(Savez hemijskih inženjera, Beograd, 2012)
Extensive biochemical and pharmacological studies have determined three different subtypes of imidazoline receptors: I1-imidazoline receptors (I1-IR) - involved in central inhibition of sympathicus that produce hypotensive ...
Optimization of Chromatographic Separation of Acetylsalicylic Acid, Amlodipine, Impurity a of Amlodipine, and Atenolol in Hydrophilic Interaction Liquid Chromatography Employing DoE Methodology
(Taylor & Francis Inc, Philadelphia, 2015)
The retention behavior of substances in hydrophilic interaction liquid chromatography (HILIC) is difficult to predict. Mixture investigated in this paper consists of acetylsalicylic acid, amlodipine, impurity A of amlodipine, ...
Essential oil of Calamintha sylvatica Bromf. and Calamintha vardarensis Silic
(Allured Publ Corp, Carol Stream, 2004)
The essential oil of three populations of Calamintha sylvatica Bromf. native to the mountain region of southwestern Serbia and one population of Calamintha vardarensis Silic from southern former Yugoslav Republic of Macedonia ...
Kinetic Determination of Trace Levels of Selenium(IV) and Total Selenium by Nile Blue A/Hydrogen Peroxide Method
(Springer New York, 1998)
A kinetic method for the determination of selenium(IV) traces is proposed, based on its inhibitory action on the oxidation of Nile Blue A by hydrogen peroxide in phosphate buffer (pH 10.5). A linear dependence was established ...