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An investigation into the influence of hydrogel composition on swelling behavior and drug release from poly(acrylamide-co-itaconic acid) hydrogels in various media
(Taylor & Francis Ltd, Abingdon, 2006)
The hydrogels prepared by free radical copolymerization of acrylamide and itaconic acid were investigated with regard to their composition and crosslinking degree to find materials with satisfactory swelling and drug release ...
LC determination of lercanidipine and its impurities using DryLab software and experimental design procedures
(Vieweg, Wiesbaden, 2008)
The main objective in all optimization procedures is to define the most appropriate conditions for rapid, sensitive, precise, and reproducible analysis, as economically as possible. Experimental design and DryLab optimization ...
Application of mathematical modeling for the development and optimization formulation with bioactive copper complex
(Taylor & Francis Ltd, Abingdon, 2013)
New formulation for treatment a copper deficiency in human organism was developed and optimized by application of mathematical modeling. This formulation contained copper (II) complex with polysaccharide pullulan, as active ...
Theoretical and empirical models in hydrophilic interaction liquid chromatography
(Taylor & Francis Inc, Philadelphia, 2014)
Hydrophilic interaction liquid chromatography (HILIC) has found application in the determination of polar molecules. This alternative type of chromatography has become increasingly popular in the last five years and a ...
Determination of Bupropion and Its Impurities via a Chaotropic Chromatography Method Following Analytical Quality-by-Design Principles for Method Development
(MDPI, 2022)
A novel chaotropic chromatography method for the quantitative determination of bupropion and its impurities, following analytical quality-by-design (AQbD) principles, is presented. The analytical target profile (ATP) was ...
Towards satisfying performance of an O/W cosmetic emulsion: screening of reformulation factors on textural and rheological properties using general experimental design
(Wiley, Hoboken, 2017)
OBJECTIVE: Consumers' demand for improved products' performance, alongside with the obligation of meeting the safety and efficacy goals, presents a key reason for the reformulation, as well as a challenging task for ...
Ultra-performance liquid chromatography tandem mass spectrometry for the rapid, simultaneous analysis of ziprasidone and its impurities
(Wiley, Hoboken, 2019)
The separation and characterization of the unknown degradation product of second-generation antipsychotic drug ziprasidone are essential for defining the genotoxic potential of the compound. The aim of this study was to ...
RP HPLC investigation of some diuretics using exsperimental design / RP HPLC ispitivanje pojedinih diuretika primenom eksperimentalnog dizajna
(Savez farmaceutskih udruženja Srbije, Beograd, 2002)
Diuretics are chemicals that increase the rate of urine formation. This pharmacologic property has led to the use of diuretics in the treatment of edematous conditions resulting from a variety of causes (e.g. congestive ...
Influence of pH and agitation intensity on drug dissolution from tablets evaluated by means of factorial design
(Editio Cantor Verlag GmbH, 2001)
Dissolution rate of a drug substance can be strongly influenced by the experimental conditions employed, among which agitation intensity and pH value were recognized as the most important. A complete two-factor, three-level ...
Influence of pH and agitation intensity on drug dissolution from tablets evaluated by means of factorial design
(ECV-Editio Cantor Verlag Medizin Naturwissenschaften, Aulendorf, 2001)
Dissolution rate of a drug substance can be strongly influenced by the experimental conditions employed, among which agitation intensity and pH value were recognized as the most Important. A complete two-factor, three-level ...