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Comparative evaluation of mechanical properties of lactose-based excipients co-processed with lipophilic glycerides as meltable binders
(Elsevier B.V., 2022)
The introduction of the high-speed tableting machines and the lack of excipients with good flow and compaction properties required for direct compression process have increased research interest in the development of ...
Body mass index is independently associated with xanthine oxidase activity in overweight/obese population
(Springer International Publishing, 2020)
Purpose: The pathophysiological mechanism of the relationship between xanthine oxidase (XO) activity and obesity has not been completely elucidated. Since inflammation and oxidative stress are regarded as key determinants ...
Modification of Keggin anion structure with ion beams—A new spectroscopic insights into the effects of keV- and MeV-ion beam irradiation on 12-tungstophosphoric acid
(John Wiley and Sons Ltd, 2022)
Ion beam irradiation is a versatile tool for structural modification andengineering of new materials. In this study, 12-tungstophosphoric acid (WPA)films of different thickness were spin-coated on platinized silicon substrate ...
Antioxidant, antigenotoxic and cytotoxic activity of essential oils and methanol extracts of hyssopus officinalis l. Subsp. aristatus (godr.) nyman (lamiaceae)
(MDPI AG, 2021)
Abstract:Hyssopus officinalisL. is a well-known aromatic plant used in traditional medicine and the foodand cosmetics industry. The aim of this study is to assess the antioxidant, genotoxic, antigenotoxic andcytotoxic ...
B-cell response to seasonal influenza vaccine in mice is amenable to pharmacological modulation through β-adrenoceptor
(Elsevier Inc., 2022)
Aims: Given that deprivation of noradrenaline acting on lymphocytes through β-adrenoceptor influences anti- body response, the effects of propranolol treatment beginning two days before immunization with quadrivalent ...
A comprehensive study on retention of selected model substances in β-cyclodextrin-modified high performance liquid chromatography
(Elsevier B.V., 2021)
The quantitative structure-retention relationship (QSRR) models are not only employed in retention behaviour prediction, but also in an in-depth understanding of complex chromatographic systems. The goal of the present ...
Antiallergic Treatment of Bariatric Patients: Potentially Hampered Solubility/Dissolution and Bioavailability of Loratadine, but Not Desloratadine, Post-Bariatric Surgery
(American Chemical Society, 2022)
Gastrointestinal anatomical/physiological changes after bariatric surgery influence variables affecting the fate of drugs after ingestion, and medication management of these patients requires a thorough and complex mechanistic ...
Curcumin-loaded low-energy nanoemulsions: Linking EPR spectroscopy-analysed microstructure and antioxidant potential with in vitro evaluated biological activity
(Elsevier B.V., 2020)
The objective of this work was to investigate and profoundly characterize low-energy nanoemulsions as multifunctional carriers, with slight reference to dermal administration. An evidence-based approach was offered for ...
MFI, BEA and FAU zeolite scavenging role in neonicotinoids and radical species elimination
(The Royal Society of Chemistry, 2022)
Ecotoxicity caused by neonicotinoid pesticides is largely due to oxidative stress on non-target species. Due to the fact that reactive radical species reach the environment, materials intended for pesticide removal should ...
Improving tableting performance of lactose monohydrate by fluid-bed melt granulation co-processing
(MDPI, 2021)
Co-processing is commonly used approach to improve functional characteristics of pharmaceutical excipients to become suitable for tablet production by direct compression. This study aimed to improve tableting characteristics ...