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Prikaz rezultata 1-10 od 34
The effect of pre-treatment with l-name on glutathione and glutathione peroxidase in parquat-induced neurotoxicity in rat striatum / Efekat predtretmana sa l-name na glutation i glutation peroksidazu u strijatumu pacova na neurotoksičnost izazvanu parakvatom
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Contact herbicide paraquat (DQ) is bipyridylium compound, which undergoes redox metabolism; hence enlarged in humans radical production mediated its toxicity. Target organs of systemic effect of PQ poisoning are lung and ...
Purification of biological samples and validation of bioanalytical HPLC methods for analysis of drugs and their metabolites / Priprema biološkog materijala i validacija bioanalitičkih HPLC metoda za ispitivanje lekova i njihovih metabolite
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Purification of biological matrix prior to HPLC analysis has been complex procedure and source of great variability of analytical results. The most used biological matrixes used for analysis are plasma, serum, urine and ...
Mechanistic simulation of carbamazepine absorption after oral administration of immediate release tablets / In silico predviđanje apsorpcije karbamazepina nakon oralne primene tableta sa trenutnim oslobađanjem
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The main prerequisite to establish quantitative in vitro-in vivo correlation (IVIVC) and define biorelevant in vitro methodology is to identify drug dissolution profile in vivo. When intravenous data are not available due ...
Psychoactive controlled substances: Current situation in the world / O psihoaktivnim kontrolisanim supstancama - situacija u svetu
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Although the psychoactive substances are strictly controlled in most of the countries in the world, their abuse is still very present, as confirmed by the data from the year of 2009 when over 200 million drug addicts were ...
Adverse effects and toxicity of analgesics / Neželjeni efekti i toksičnost analgetika
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Even though among the most widely used analgoantipiretics with confirmed pharmacological effects, acetylsalicylic acid, paracetamol and ibuprofen may be the cause of poisonings and even death. Acetylsalicylic acid and ...
Pharmacokinetic aspects in dosing regimen in paediatrics / Farmakokinetički aspekti doziranja lekova u pedijatriji
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Clinical trials in paediatric patients are limited due to certain practical, ethical and regulatory aspects. Accordingly, after performing pharmacokinetic (PK) and efficacy/safety clinical trials in adults, clinical trials ...
Oxidative and nitrosative stress: Mediators of diquat neurotoxicity / Oksidativni i nitrozativni stres - medijatori neurotoksičnosti dikvata
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
Most commonly observed central nervous system (CNS) effects induced by systemic toxicity of herbicide diquat (DQ) are general depression and lethargy. Generally, it is accepted that DQ exerts its toxicity through the ...
Biologics: Pharmaceutical-technological specificities / Biološki lekovi - farmaceutsko-tehnološke specifičnosti
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The field of pharmaceutical biotechnology is developing rapidly. For those working in the field of pharmacy and pharmaceutical sciences, completely new and novel techniques and product appear at a rapid pace, with an almost ...
Analysis, adaptation and validation of the instrument for the competence evaluation of the pharmacists in community pharmacies / Analiza, adaptacija i validacija dokumenta za procenu kompetencija farmaceuta
(Savez farmaceutskih udruženja Srbije, Beograd, 2012)
The competency of a pharmacist is one of the fundamental preconditions for high quality pharmaceutical care provision. The General Lever Framework (GLF), which was developed by a group of British experts (Competency ...
Seeds and flowers of chestnut trees in urban areas: A municipal waste or a raw material? / Seme i cvet kestena u gradskim područjima - komunalni otpad ili sirovina?
(Institut za proučavanje lekovitog bilja Dr Josif Pančić, Beograd, 2012)
This study deals with the examination of total aescin content in flowers and seeds of Aesculus hippocastanum L. and Aesculus x carnea Hayne (Hippocastanaceae), collected in urban areas, as well as the content of Pb, Cd and ...