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Prikaz rezultata 101-106 od 106
Synthesis, cytotoxicity and computational study of novel protoberberine derivatives
(Srpsko hemijsko društvo, Beograd, 2016)
A novel and efficient synthetic route was developed for the preparation of protoberberine derivatives. A methodology, designed primarily to control the substitution patterns on the terminal rings, was used to access a small ...
Application of liquid chromatography in defining the interaction of newly synthesized chalcones and related compounds with human serum albumin / Примена течне хроматографије у дефинисању интеракција новосинтетисаних халкона и сродних супстанци са хуманим серумским албуминима
(Srpsko hemijsko društvo, Beograd, 2023)
Defining the interaction of newly synthesized compounds with plasma proteins is an important step in the drug development process. Chromatographic techniques can be successfully used in predicting the biopharmaceutical ...
Protein degradation induced by PROTAC molecules as an emerging drug discovery strategy / Деградација протеина индукована PROTAC молекулима као нова стратегија у развоју лекова
(Serbian Chemical Society, 2022)
The traditional concept of drug discovery is based on the occupancydriven pharmacology model. It implies the development of inhibitors occupying binding sites that directly affect protein functions. Therefore, proteins ...
The importance of the accuracy of the experimental data for the prediction of solubility / Važnost preciznosti eksperimentalnih podataka za procenu rastvorljivosti
(Srpsko hemijsko društvo, Beograd, 2010)
Aqueous solubility is an important factor influencing several aspects of the pharmacokinetic profile of a drug. Numerous publications present different methodologies for the development of reliable computational models for ...
Optimization of chromatographic separation of aripiprazole and impurities: Quantitative structure-retention relationship approach / Оптимизација хроматографског раздвајања арипипразола и нечистоћа: приступ квантификовања односа структуре и ретенционог понашања
(Serbian Chemical Society, 2022)
A new optimization strategy based on the mixed quantitative struc- ture–retention relationship (QSRR) model is proposed for improving the RP- HPLC separation of aripiprazole and its impurities (IMP A-E). Firstly, experi- ...
The influence of different enzymatic preparations and skin contact time on aromatic profile of wines produced from autochthonous grape varieties Krstac and Zizak / Утицај различитих ензимских третмана и времена контакта покожице на ароматске профиле вина произведених од аутохтоних сорти грожђа Крстач и Жижак
(Serbian Chemical Society, 2023)
This study aimed to show aromatic profile of wines produced from two autochthonous grape cultivars Krstač (K) and Žižak (Z). During the wine production two enzymatic preparations (EP) Lallzyme cuvee blanc (CB) and Lallzyme ...