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Premature centromere separation syndromes: A manifestation of genome instability?
(Macedonian Academy of Sciences and Arts, 2000)
Premature centromere separation (PCS) syndromes strongly support evidence that spatial and temporal organization of the cell cycle is crucial for maintaining genomic stability. To see if PCS as a genomic instability state ...
Determination of fluocortolone pivalate and fluocortolone hexanoate in suppositories using reverse-phase HPLC
(Elsevier Science Sa, Lausanne, 2000)
Fluocortolone and its esters are synthetic corticosteroids used topically in the treatment of various skin disorders. A method that can be successfully used for the separation and determination of fluocortolone pivalate ...
The retention behavior of several semisynthetic cephalosporins in planar chromatography
(Springer Hungarica Kiado Kft, Budapest, 2000)
The chromatographic behavior of cephalexine, cefaclore, ceftriaxone, cefiuime, and cefotaxime has been investigated on silica gel layers with binary mobile phases containing different amounts of organic modifier. The ...
Prediction of drug transfer into human milk from theoretically derived descriptors
(Elsevier Science BV, Amsterdam, 2000)
The goal of this study was to develop a genetic neural network (GNN) model to predict the degree of drug transfer into breast milk, depending on the molecular structure descriptors, and to compare it with the current model. ...
Castration of sexually immature rats affects sympathetic innervation of the adult thymus
(Karger, Basel, 2000)
It has been hypothesized that maturational processes within the hypothalamo-pituitary-gonadal (HPG) axis and thymus are reciprocally regulated via neural pathways. To test this hypothesis, in the thymi of adult rats ...
UV derivative spectrophotometric study of the photochemical degradation of nisoldipine
(Elsevier Science Sa, Lausanne, 2000)
The photodecomposition of nisoldipine ((+/-)3-isobutyl-5-methyl-1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-pyridine-3,5-dicarboxylate), whereby its 4-(2-nitrosophenyl) pyridine analogue is obtained as the photolytic product, ...
Statistical optimization of a reversed-phase liquid chromatographic method for the analysis of amiloride and hydrochlorothiazide in tablets
(Pergamon-Elsevier Science Ltd, Oxford, 2000)
A method has been developed for the separation of hydrochlorothiazide and amiloride by high-performance liquid chromatographic (HPLC) method on a C-18 column with detection at 280 nm. The optimal conditions of separation ...
Biochemical evaluation of patients with acute pancreatitis
(Walter de Gruyter & Co, Berlin, 2000)
In this study we determined the clinical accuracy of alpha (2)-macroglobulin, alpha -amylase, C-reactive protein, lipase, non-esterified fatty acids, pancreatic alpha -amylase and phospholipase A in the diagnosis and ...
Selective indicator reaction for kinetic determination of traces of manganese(II), ribavirin and tiazofurin
(Springer-Verlag Wien, Vienna, 2000)
In this work it was established that, in the presence of ammonium carbonate, traces of manganese(II) catalyse the oxidation of Nile Blue A by hydrogen peroxide, which enables its: kinetic determination in the concentration ...
Spectrophotometric determination of ciprofloxacin in serum using iron(III) ion as chromogenic agent
(Marcel Dekker Inc, New York, 2000)
An analytical procedure for the determination of ciprofloxacin in serum without previous extraction has been developed. The determination was carried out using iron(III) nitrate as chromogenic agent, with the addition of ...