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Justification of metformin hydrochloride biowaiver criteria based on bioequivalence study
(ECV-Editio Cantor Verlag Medizin Naturwissenschaften, Aulendorf, 2010)
The Biopharmaceutics Classification System (BCS) represents the framework for predicting the intestinal drug absorption based on its solubility and intestinal permeability. Recent research has lead to the use of in vitro ...
TLC Retention Behavior of Brodifacoum, Bromadiolone, and Coumatetralyl and their Impurities on Different Adsorbents
(Akademiai Kiado Zrt, Budapest, 2009)
The chromatographic behavior of three biocidal technical materials, rodenticide active ingredients brodifacoum, bromadiolone, and coumatetralyl, and impurities present in the technical material was investigated by both ...
GC-ECD Determination of Lindane and Its Impurity alpha-HCH in Pharmaceutical Products
(Springer Heidelberg, Heidelberg, 2010)
A method was developed to determine lindane (gamma-HCH), the widely used organochlorine pesticide, and its impurity alpha-HCH in bulk and pharmaceutical products (shampoo, gel and emulsion). The system was able to successfully ...
Forced degradation studies of simvastatin using microemulsion liquid chromatography
(Taylor & Francis Inc, Philadelphia, 2010)
In this paper, the definition of simvastatin degradation profile by microemulsion liquid chromatography (MELC) is presented. The aim of the study was to investigate simvastatin stability after various stress tests, such ...
Phenotypes and serum level of alpha-1-antitrypsin in lung cancer
(Balkan Union of Oncology (B.U.ON.), 2011)
Propose: Alpha-1-antitrypsin (AAT) as the major circulating inhibitor of proteases has important role in protease-antiprotease homeostasis. Recent studies have confirmed its antiapoptotic role. AAT is a highly polymorphic ...
Should we routinely measure low-density and high-density lipoprotein subclasses?
(Clin Lab Publ, Heidelberg, 2009)
Low-density lipoprotein (LDL) and high-density lipoprotein (HDL) plasma populations are composed of heterogeneous subfractions that are different in size, density and protein/lipid content. There is increasing evidence ...
Relation Between 25(OH)-Vitamin D Deficiency and Markers of Bone Formation and Resorption in Haemodialysis Patients
(Clin Lab Publ, Heidelberg, 2009)
Deficient serum 25-hydroxyvitamin D [25(OH)D] may contribute to the impaired bone turnover of end stage renal disease patients. In 112 hemodialysed patients we analysed the relation between 25(OH)D and bone alkaline ...
Sex bias in mouse humoral immune response to influenza vaccine depends on the vaccine type
(Academic Press Ltd- Elsevier Science Ltd, London, 2018)
The study explored influence of biological sex on development of humoral immune response to seasonal trivalent whole inactivated virus (WIV) and split virus (SV) influenza vaccines in outbred Swiss mouse model. To this ...
An investigation into effects of In Vitro Test condition on the release properties of theophylline from HPMC matrices using factorial design
(Pharmaceutical Soc Korea, Seoul, 2009)
The purpose of this study was to investigate the effect of various in vitro test conditions, on the release properties of theophylline (TP) from aminophylline (AP) matrices based on different hydroxypropylmethylcellulose ...
Composition of the essential oils from the aerial parts of five wild growing Valeriana species
(Allured Publ Corp, Carol Stream, 2007)
The essential oils obtained by hydrodistillation from aerial parts of five Valeriana species, growing wild in Serbia and Montenegro, Valeriana officinalis L., V pancicii Halacsy et Bald., V. bertiscea Pancic, V. montana ...