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Recommedition for apllication and determination tumor markers of neuroendocrine system / Preporuke za primenu i odredivanje tumorskih markera kod neoplazmi neuroendokrinog sistema
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2007)
Neuroendocrine tumors derive from neuroendocrine cells, which upon specific stimulation secrete stimulation secrete hormones regulating various bodily functions. We will discuss the group of neuroendocrine tumors which is ...
Guidelines for the use of tumor markers in breast cancer / Vodiči za primenu tumorskih markera kod karcinoma dojke
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2007)
The best-validated markers in breast cancer are all tissue based and include estrogen receptors (ER), progesteron receptors (PR), HER-2, urokinase plasminogen activator (uPA) and plasminogen activator inhibitor 1 (PAI-1). ...
Oxidative stress: Clinical diagnostic significance
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2008)
Elevated free radical production and/or insufficient antioxidative defense results in cellular oxidant stress responses. Sustained and/or intense oxidative insults can overcome cell defenses resulting in accumulated damage ...
Isoelectrofocusing and PCR Amplification-Reverse Hybridization Assay in Evaluation of Alpha-1-Antitrypsin Deficiency
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2009)
Alpha-1-antitrypsin deficiency is a potentially lethal genetic disorder, which has pulmonary and liver manifestations. The standardized biochemical and molecular diagnostic protocol for detection of clinically relevant ...
Incidence of hyperhomocysteinemia and Mthfr C677T polymorphism among young patients with acute myocardial infarction
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2009)
Hyperhomocysteinemia is considered an independent risk factor for premature cardiovascular disease. Mutation MTHFR C677T reduces the activity of methylenetetra-hydrofolatereductase and may cause hyperhomocysteinemia. ...
Application of six sigma in control of health laboratories / Primena »six sigma« u kontroli kvaliteta zdravstvenih laboratorija
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2007)
The goal of every operation or production system is to generate a useful product. Most quality-control methods were initially developed to aid manufacturing. This is not surprising because high volume production typically ...
Comparison of two different methods for cardiovascular risk assessment: Framingham risk score and SCORE system / Poređenje dve metode procene kardiovaskularnog rizika - 'Framingham' rizik skor i 'Score' sistem
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2007)
Numerous studies have shown that the major risk factors for coronary heart disease (cigarette smoking, hypertension, elevated serum total cholesterol and low-density lipoprotein cholesterol - LDL, low serum high-density ...
Methotrexate-associated biochemical alterations in a patient with chronic neurotoxicity
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2009)
Intrathecal and/or high-dose intravenous administration of methotrexate (MTX) in the treatment of malignancies such as acute lymphoblastic leukaemia (ALL) has been associated with cases of mild to severe neurotoxicity. The ...
Renal function: Estimation of glomerular filtration rate / Funkcija bubrega - Procena brzine glomerularne filtracije
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2007)
The glomerular filtration rate (GFR) is widely accepted as the best overall measure of kidney function. American National Kidney Foundation guidelines define chronic kidney disease (CKD) by either a GFR of less than 60 ...
Hyperhomocysteinemia and smoking in primary antiphospholipid syndrome
(Društvo medicinskih biohemičara Srbije, Beograd i Versita, 2009)
The thrombotic tendency in anti phospholipid syndrome (APS) shares several pathways with atherosclerosis. Atherothrombosis (atherosclerosis superimposed with thromboses) is influenced by nonmodifiable and some modifiable ...